This is a very interesting statement, and in most King James Bibles the margin reads "again" as being "from above". In Strong's Greek dictionary, # 509, the word is "Anothen", "from above". You will never understand this statement that Jesus made unless you understand what it means to be "born from above." In a later verse, it is documented that you must be "born from above", or your soul will be lost for eternity. So you see its vital for you to come through a woman unless God has chosen you not to, beings like Michael and Gabriel....
The church world has their sayings and songs that "Ye must be born again", and yet these verses they sin miss the mark, because they do not understand what it means to be "born from above" [born again]. This is part of God's plan that everyone [every soul] be born of woman, from above. For documentation we find in the Book of Jude whereby the penalty of the fallen angels is given, in as much as they left their place of habitation. Angels are to inhabit heaven, or paradise at this time, in the flesh age.
This will surely lead into a study of who chose not to be born through a woman.... Jude
Our spirits existed long before our bodies. Now we're stuck here! Lol, well, for a time. Lol.